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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDFY4
All Species:
4.55
Human Site:
S1493
Identified Species:
12.5
UniProt:
Q6ZS81
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZS81
NP_065996.1
3184
353610
S1493
H
L
L
E
I
L
Q
S
P
R
E
G
P
R
N
Chimpanzee
Pan troglodytes
XP_507779
2481
275849
M903
S
S
E
S
K
E
E
M
F
L
K
L
G
P
D
Rhesus Macaque
Macaca mulatta
XP_001113742
1569
176214
Dog
Lupus familis
XP_543897
3176
353689
S1505
H
L
V
E
I
L
R
S
P
R
E
G
P
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6VNB8
3508
392319
E1529
H
F
I
E
L
L
T
E
S
S
E
A
S
K
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507227
1895
210959
P317
L
E
S
S
G
G
Y
P
L
L
L
K
V
L
L
Chicken
Gallus gallus
XP_420572
3527
395492
E1528
H
F
I
E
L
L
T
E
S
S
E
A
A
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19317
2507
281187
I929
L
K
V
I
A
H
V
I
S
Q
C
E
E
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25356
2167
250854
G589
D
Q
S
S
L
A
S
G
G
L
E
I
I
R
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73
47.3
80.8
N.A.
34.4
N.A.
N.A.
38.2
33.9
N.A.
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
100
74.7
48.2
87.2
N.A.
53.3
N.A.
N.A.
46.5
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
38.5
N.A.
P-Site Identity:
100
0
0
86.6
N.A.
33.3
N.A.
N.A.
0
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
20
0
100
N.A.
53.3
N.A.
N.A.
0
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
0
0
0
0
0
23
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
12
12
45
0
12
12
23
0
0
56
12
12
0
12
% E
% Phe:
0
23
0
0
0
0
0
0
12
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
12
12
0
12
12
0
0
23
12
0
0
% G
% His:
45
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
12
23
0
0
12
0
0
0
12
12
0
0
% I
% Lys:
0
12
0
0
12
0
0
0
0
0
12
12
0
23
0
% K
% Leu:
23
23
12
0
34
45
0
0
12
34
12
12
0
12
12
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% N
% Pro:
0
0
0
0
0
0
0
12
23
0
0
0
23
12
0
% P
% Gln:
0
12
0
0
0
0
12
0
0
12
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
23
0
0
0
34
0
% R
% Ser:
12
12
23
34
0
0
12
23
34
23
0
0
12
12
0
% S
% Thr:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% T
% Val:
0
0
23
0
0
0
12
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _